Gas6/Axl Axis Activation Dampens the Inflammatory Response in Osteoarthritic Fibroblast-like Synoviocytes and Synovial Explants

Osteoarthritis (OA) is the most prevalent joint disease, and it is characterized by cartilage degeneration, synovitis, and bone sclerosis, resulting in swelling, stiffness, and joint pain. TAM receptors (Tyro3, Axl, and Mer) play an important role in regulating immune responses, clearing apoptotic c...

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Detalhes bibliográficos

Principais autores:	Juliana P. Vago, Natália Valdrighi, Esmeralda N. Blaney-Davidson, Daniel L. A. H. Hornikx, Margot Neefjes, María E. Barba-Sarasua, Nathalie G. M. Thielen, Martijn H. J. van den Bosch, Peter M. van der Kraan, Marije I. Koenders, Flávio A. Amaral, Fons A. J. van de Loo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-05-01
Colecção:	Pharmaceuticals
Assuntos:	osteoarthritis TAM receptors Gas6 synovitis
Acesso em linha:	https://www.mdpi.com/1424-8247/16/5/703
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