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Role of RB1 in neurodegenerative diseases: inhibition of post-mitotic neuronal apoptosis via Kmt5b

Abstract During the development of the vertebrate nervous system, 50% of the nerve cells undergo apoptosis shortly after formation. This process is important for sculpting tissue during morphogenesis and removing transiently functional cells that are no longer needed, ensuring the appropriate number...

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Bibliografiske detaljer
Principais autores: Shuang Zhao, Guiling Mo, Qiang Wang, Jin Xu, Shihui Yu, Zhibin Huang, Wei Liu, Wenqing Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2024-04-01
Serier:Cell Death Discovery
Online adgang:https://doi.org/10.1038/s41420-024-01955-y
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