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Identification of tyrosine brominated extracellular matrix proteins in normal and fibrotic lung tissues

Peroxidasin (PXDN) is a secreted heme peroxidase that catalyzes the oxidative crosslinking of collagen IV within the extracellular matrix (ECM) via intermediate hypobromous acid (HOBr) synthesis from hydrogen peroxide and bromide, but recent findings have also suggested alternative ECM protein modif...

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Autori principali: Litiele Cezar Cruz, Aida Habibovic, Bianca Dempsey, Mariana P. Massafera, Yvonne M.W. Janssen-Heininger, Miao-chong Joy Lin, Evan T. Hoffman, Daniel J. Weiss, Steven K. Huang, Albert van der Vliet, Flavia C. Meotti
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2024-05-01
Serie:Redox Biology
Soggetti:
Peroxidasin
Hypobromous acid
Bromotyrosine
Laminin
Collagen
Tubulointerstitial nephritis antigen-like 1
Accesso online:http://www.sciencedirect.com/science/article/pii/S2213231724000788
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