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ZNF143 deletion alters enhancer/promoter looping and CTCF/cohesin geometry

Summary: The transcription factor ZNF143 contains a central domain of seven zinc fingers in a tandem array and is involved in 3D genome construction. However, the mechanism by which ZNF143 functions in chromatin looping remains unclear. Here, we show that ZNF143 directionally recognizes a diverse ra...

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Bibliographic Details
Main Authors: Mo Zhang, Haiyan Huang, Jingwei Li, Qiang Wu
Format: Artigo
Language:Inglês
Published: Elsevier 2024-01-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723016741
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