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A1-reprogrammed mesenchymal stromal cells prime potent antitumoral responses

Summary: Mesenchymal stromal cells (MSCs) have been modified via genetic or pharmacological engineering into potent antigen-presenting cells-like capable of priming responding CD8 T cells. In this study, our screening of a variant library of Accum molecule revealed a molecule (A1) capable of eliciti...

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Autori principali: Marina Pereira Gonçalves, Roudy Farah, Jean-Pierre Bikorimana, Jamilah Abusarah, Nehme EL-Hachem, Wael Saad, Sebastien Talbot, Daniela Stanga, Simon Beaudoin, Sebastien Plouffe, Moutih Rafei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2024-03-01
Serie:iScience
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Classification Description
Immunology
Pharmaceutical engineering
Cancer
Accesso online:http://www.sciencedirect.com/science/article/pii/S2589004224004693
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