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Brilacidin, a novel antifungal agent against Cryptococcus neoformans

ABSTRACT Cryptococcus neoformans causes cryptococcosis, one of the most prevalent fungal diseases, generally characterized by meningitis. There is a limited and not very effective number of drugs available to combat this disease. In this manuscript, we show the host defense peptide mimetic brilacidi...

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Autori principali: Camila Diehl, Camila Figueiredo Pinzan, Patrícia Alves de Castro, Endrews Delbaje, Laura C. García Carnero, Eddy Sánchez-León, Kabir Bhalla, James W. Kronstad, Dong-gyu Kim, Tamara L. Doering, Sondus Alkhazraji, Nagendra N. Mishra, Ashraf S. Ibrahim, Mami Yoshimura, Luis Alberto Vega Isuhuaylas, Lien Thi Kim Pham, Yoko Yashiroda, Charles Boone, Thaila Fernanda dos Reis, Gustavo H. Goldman
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2024-07-01
Serie:mBio
Soggetti:
Cryptococcus neoformans
brilacidin
antifungal agent
caspofungin
Accesso online:https://journals.asm.org/doi/10.1128/mbio.01031-24
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