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Brilacidin, a novel antifungal agent against Cryptococcus neoformans

ABSTRACT Cryptococcus neoformans causes cryptococcosis, one of the most prevalent fungal diseases, generally characterized by meningitis. There is a limited and not very effective number of drugs available to combat this disease. In this manuscript, we show the host defense peptide mimetic brilacidi...

Ausführliche Beschreibung

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Hauptverfasser: Camila Diehl, Camila Figueiredo Pinzan, Patrícia Alves de Castro, Endrews Delbaje, Laura C. García Carnero, Eddy Sánchez-León, Kabir Bhalla, James W. Kronstad, Dong-gyu Kim, Tamara L. Doering, Sondus Alkhazraji, Nagendra N. Mishra, Ashraf S. Ibrahim, Mami Yoshimura, Luis Alberto Vega Isuhuaylas, Lien Thi Kim Pham, Yoko Yashiroda, Charles Boone, Thaila Fernanda dos Reis, Gustavo H. Goldman
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2024-07-01
Schriftenreihe:mBio
Schlagworte:
Cryptococcus neoformans
brilacidin
antifungal agent
caspofungin
Online-Zugang:https://journals.asm.org/doi/10.1128/mbio.01031-24
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