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The PRMT5-LSD1 axis confers Slug dual transcriptional activities and promotes breast cancer progression

Abstract Background Downregulation of epithelial markers and upregulation of mesenchymal markers are the characteristics of the epithelial to mesenchymal transition (EMT) program, which provides the metastatic advantage of breast cancer. However, the mechanism underlying the switch of EMT markers re...

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Autori principali: Jianchao Zhang, Xiaokai Fan, Yunfan Zhou, Liang Chen, Hai Rao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2022-06-01
Serie:Journal of Experimental & Clinical Cancer Research
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Accesso online:https://doi.org/10.1186/s13046-022-02400-7
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