A forebrain-hypothalamic ER stress driven circuit mediates hepatic steatosis during obesity

Objective: Non-alcoholic fatty liver disease (NAFLD) affects 1 in 3 adults and contributes to advanced liver injury and cardiometabolic disease. While recent evidence points to involvement of the brain in NAFLD, the downstream neural circuits and neuronal molecular mechanisms involved in this respon...

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Detalles Bibliográficos

Principais autores:	Katherine Blackmore, Claire J. Houchen, Hayk Simonyan, Hovhannes Arestakesyan, Alyssa K. Stark, Samantha A. Dow, Han Rae Kim, Jin Kwon Jeong, Anastas Popratiloff, Colin N. Young
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2024-01-01
Series:	Molecular Metabolism
Assuntos:	Non-alcoholic fatty liver disease Subfornical organ Paraventricular nucleus of the hypothalamus Endoplasmic reticulum Unfolded protein response Sympathetic nervous system
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2212877823001928
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