Central Angiotensin II type 1 receptor deficiency alleviates renal fibrosis by reducing sympathetic nerve discharge in nephrotoxic folic acid–induced chronic kidney disease

Background Fibrosis after nephrotoxic injury is common. Activation of the paraventricular nucleus (PVN) renin-angiotensin system (RAS) and sympathetic nervous system (SNS) are common mechanism of renal fibrosis. However, there have limited knowledge about which brain regions are most affected by Ang...

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Hlavní autoři:	Qijun Wan, Zhichen Yang, Lingzhi Li, Liling Wu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	PeerJ Inc. 2024-09-01
Edice:	PeerJ
Témata:	Fibrosis Sympathetic nerve activity Paraventricular nucleus Rostral ventrolateral medulla Angiotensin II type 1a receptors
On-line přístup:	https://peerj.com/articles/18166.pdf
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