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Central Angiotensin II type 1 receptor deficiency alleviates renal fibrosis by reducing sympathetic nerve discharge in nephrotoxic folic acid–induced chronic kidney disease

Background Fibrosis after nephrotoxic injury is common. Activation of the paraventricular nucleus (PVN) renin-angiotensin system (RAS) and sympathetic nervous system (SNS) are common mechanism of renal fibrosis. However, there have limited knowledge about which brain regions are most affected by Ang...

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Principais autores: Qijun Wan, Zhichen Yang, Lingzhi Li, Liling Wu
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2024-09-01
coleção:PeerJ
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Acesso em linha:https://peerj.com/articles/18166.pdf
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