Rapid and selective detection of fatty acylated proteins using ω-alkynyl-fatty acids and click chemistry[S]

Progress in understanding the biology of protein fatty acylation has been impeded by the lack of rapid direct detection and identification methods. We first report that a synthetic ω-alkynyl-palmitate analog can be readily and specifically incorporated into GAPDH or mitochondrial 3-hydroxyl-3-methyl...

Cijeli opis

Bibliografski detalji

Glavni autori:	Megan C. Yap, Morris A. Kostiuk, Dale D.O. Martin, Maneka A. Perinpanayagam, Pieter G. Hak, Anjaiah Siddam, Janaki R. Majjigapu, Gurram Rajaiah, Bernd O. Keller, Jennifer A. Prescher, Peng Wu, Carolyn R. Bertozzi, John R. Falck, Luc G. Berthiaume
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2010-06-01
Serija:	Journal of Lipid Research
Teme:	myristoylation palmitoylation mitochondria membranes enzymes
Online pristup:	http://www.sciencedirect.com/science/article/pii/S0022227520410326
Oznake:	Dodaj oznaku Bez oznaka, Budi prvi tko označuje ovaj zapis!