Comparative Analysis of Click Chemistry Mediated Activity-Based Protein Profiling in Cell Lysates
Activity-based protein profiling uses chemical probes that covalently attach to active enzyme targets. Probes with conventional tags have disadvantages, such as limited cell permeability or steric hindrance around the reactive group. A tandem labeling strategy with click chemistry is now widely used...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2013-10-01
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| coleção: | Molecules |
| Assuntos: | |
| Acesso em linha: | http://www.mdpi.com/1420-3049/18/10/12599 |
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