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Clinical characteristics and host immunity responses of SARS-CoV-2 Omicron variant BA.2 with deletion of ORF7a, ORF7b and ORF8

Abstract Background The pathogenicity and virulence of the Omicron strain have weakened significantly pathogenesis of Omicron variants. Accumulating data indicated accessory proteins play crucial roles in host immune evasion and virus pathogenesis of SARS-CoV-2. Therefore, the impact of simultaneous...

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Autori principali: Zhizhong Tang, Pei Yu, Qianfang Guo, Mingxiao Chen, Yu Lei, Lei Zhou, Weikang Mai, Lu Chen, Min Deng, Weiya Kong, Chuanying Niu, Xiaoli Xiong, Wenrui Li, Chunbo Chen, Changchun Lai, Qian Wang, Baisheng Li, Tianxing Ji
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2023-05-01
Serie:Virology Journal
Soggetti:
ORF7a
ORF7b
ORF8
Cellular immunity
Humoral immunity
Cytokines
Accesso online:https://doi.org/10.1186/s12985-023-02066-3
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