Clinical characteristics and host immunity responses of SARS-CoV-2 Omicron variant BA.2 with deletion of ORF7a, ORF7b and ORF8

Abstract Background The pathogenicity and virulence of the Omicron strain have weakened significantly pathogenesis of Omicron variants. Accumulating data indicated accessory proteins play crucial roles in host immune evasion and virus pathogenesis of SARS-CoV-2. Therefore, the impact of simultaneous...

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Hlavní autoři:	Zhizhong Tang, Pei Yu, Qianfang Guo, Mingxiao Chen, Yu Lei, Lei Zhou, Weikang Mai, Lu Chen, Min Deng, Weiya Kong, Chuanying Niu, Xiaoli Xiong, Wenrui Li, Chunbo Chen, Changchun Lai, Qian Wang, Baisheng Li, Tianxing Ji
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-05-01
Edice:	Virology Journal
Témata:	ORF7a ORF7b ORF8 Cellular immunity Humoral immunity Cytokines
On-line přístup:	https://doi.org/10.1186/s12985-023-02066-3
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