Insights Into the Emergence of Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria (PNH) is a disease as simple as it is complex. PNH patients develop somatic loss-of-function mutations in phosphatidylinositol N-acetylglucosaminyltransferase subunit A gene (PIGA), required for the biosynthesis of glycosylphosphatidylinositol (GPI) anchors. Ubiqu...

詳細記述

書誌詳細

主要な著者:	Melissa A. Colden, Sushant Kumar, Bolormaa Munkhbileg, Daria V. Babushok
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2022-01-01
シリーズ:	Frontiers in Immunology
主題:	paroxysmal nocturnal hemoglobinuria PIGA GPI-anchored aplastic anemia (AA) bone marrow failure (BMF) autoimmunity
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.830172/full
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