O-GlcNAc impacts mitophagy via the PINK1-dependent pathway
BackgroundThe accumulation of dysfunctional mitochondria is an early feature of Alzheimer’s disease (AD). The impaired turnover of damaged mitochondria increases reactive oxygen species production and lowers ATP generation, leading to cellular toxicity and neurodegeneration. Interestingly, AD exhibi...
Sábháilte in:
| Príomhchruthaitheoirí: | , , , , , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
Frontiers Media S.A.
2024-08-01
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| Sraith: | Frontiers in Aging Neuroscience |
| Ábhair: | |
| Rochtain ar líne: | https://www.frontiersin.org/articles/10.3389/fnagi.2024.1387931/full |
| Clibeanna: |
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