cccDNA Surrogate MC-HBV–Based Screen Identifies Cohesin Complex as a Novel HBV Restriction FactorSummary

Background & Aims: Covalently closed circular DNA (cccDNA) of hepatitis B virus (HBV), existing as a stable minichromosome in the hepatocyte, is responsible for persistent HBV infection. Maintenance and sustained replication of cccDNA require its interaction with both viral and host proteins. Ho...

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Principais autores:	Zhuanchang Wu, Liyuan Wang, Xin Wang, Yang Sun, Haoran Li, Zhaoying Zhang, Caiyue Ren, Xiaohui Zhang, Shuangjie Li, Jinghui Lu, Leiqi Xu, Xuetian Yue, Yue Hong, Qiang Li, Haizhen Zhu, Yaoqin Gong, Chengjiang Gao, Huili Hu, Lifen Gao, Xiaohong Liang, Chunhong Ma
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2022-01-01
Serija:	Cellular and Molecular Gastroenterology and Hepatology
Teme:	Cohesin cccDNA HBx SMC3
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2352345X22001801
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