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cccDNA Surrogate MC-HBV–Based Screen Identifies Cohesin Complex as a Novel HBV Restriction FactorSummary

Background & Aims: Covalently closed circular DNA (cccDNA) of hepatitis B virus (HBV), existing as a stable minichromosome in the hepatocyte, is responsible for persistent HBV infection. Maintenance and sustained replication of cccDNA require its interaction with both viral and host proteins. Ho...

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Kaydedildi:
Asıl Yazarlar: Zhuanchang Wu, Liyuan Wang, Xin Wang, Yang Sun, Haoran Li, Zhaoying Zhang, Caiyue Ren, Xiaohui Zhang, Shuangjie Li, Jinghui Lu, Leiqi Xu, Xuetian Yue, Yue Hong, Qiang Li, Haizhen Zhu, Yaoqin Gong, Chengjiang Gao, Huili Hu, Lifen Gao, Xiaohong Liang, Chunhong Ma
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2022-01-01
Seri Bilgileri:Cellular and Molecular Gastroenterology and Hepatology
Konular:
Cohesin
cccDNA
HBx
SMC3
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2352345X22001801
Etiketler: Etiketle
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