KCNJ2/HIF1α positive-feedback loop promotes the metastasis of osteosarcoma

Abstract Background Early metastasis is a hallmark of osteosarcoma (OS), a highly common type of malignant tumor. Members of the potassium inwardly rectifying channel family exert oncogenic effects in various cancers. However, the role of the potassium inwardly rectifying channel subfamily J member...

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Hlavní autoři:	Mao Shen, Runsang Pan, Shan Lei, Lu Zhang, Changhua Zhou, Zhirui Zeng, Yingjie Nie, Xiaobin Tian
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-03-01
Edice:	Cell Communication and Signaling
Témata:	HIF1α KCNJ2 Metastasis Osteosarcoma
On-line přístup:	https://doi.org/10.1186/s12964-023-01064-w
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