Lysine lactylation regulates ATF4-mediated stress responses under glucose starvation in canine hemangiosarcoma
Excess lactate is produced in tumor cells by aerobic glycolysis and regulates gene expressions by histone lactylation. However, how histone lactylation functions under glucose-limited conditions remains unknown. Here, we show that lysine lactylation redistributes to transcription start sites (TSSs)...
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| Principais autores: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2026-02-01
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| Series: | Frontiers in Veterinary Science |
| Assuntos: | |
| Acceso en liña: | https://www.frontiersin.org/articles/10.3389/fvets.2026.1734339/full |
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