Use of Leishmania major parasites expressing a recombinant Trypanosoma cruzi antigen as live vaccines against Chagas disease

IntroductionTrypanosoma cruzi is the protozoan parasite causing Chagas disease, a Neglected Tropical Disease that affects 8 million people and causes 12,000 deaths per year, primarily because of cardiac pathology. Effective vaccination for T. cruzi remains an elusive goal. The use of a live vaccine...

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Principais autores:	Catherine W. Cai, Anne O’Shea, Christopher S. Eickhoff, Hongjie Guo, Warren G. Lewis, Stephen M. Beverley, Daniel F. Hoft
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-11-01
coleção:	Frontiers in Microbiology
Assuntos:	Chagas leishmaniasis vaccine parasite live vector
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmicb.2022.1059115/full
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