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Acrylonitrile derivatives: In vitro activity and mechanism of cell death induction against Trypanosoma cruzi and Leishmania amazonensis

Leishmaniasis and Chagas disease are parasitic infections that affect millions of people worldwide, producing thousands of deaths per year. The current treatments against these pathologies are not totally effective and produce some side effects in the patients. Acrylonitrile derivatives are a group...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Carlos J. Bethencourt-Estrella, Samuel Delgado-Hernández, Atteneri López-Arencibia, Desirée San Nicolás-Hernández, Lizbeth Salazar-Villatoro, Maritza Omaña-Molina, David Tejedor, Fernando García-Tellado, Jacob Lorenzo-Morales, José E. Piñero
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2024-04-01
Schriftenreihe:International Journal for Parasitology: Drugs and Drug Resistance
Schlagworte:
Chemotherapy
Toxicity
PCD
Leishmaniasis
Chagas
Acrylonitriles
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2211320724000125
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