Quantitative prediction of breast cancer resistant protein mediated drug‐drug interactions using physiologically‐based pharmacokinetic modeling

Abstract Quantitative assessment of drug‐drug interactions (DDIs) involving breast cancer resistance protein (BCRP) inhibition is challenged by overlapping substrate/inhibitor specificity. This study used physiologically‐based pharmacokinetic (PBPK) modeling to delineate the effects of inhibitor dru...

Повний опис

Бібліографічні деталі

Автори:	Chester Costales, Jian Lin, Emi Kimoto, Shinji Yamazaki, James R. Gosset, A. David Rodrigues, Sarah Lazzaro, Mark A. West, Michael West, Manthena V. S. Varma
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Wiley 2021-09-01
Серія:	CPT: Pharmacometrics & Systems Pharmacology
Онлайн доступ:	https://doi.org/10.1002/psp4.12672
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!