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Growth factor dependency in mammary organoids regulates ductal morphogenesis during organ regeneration

Abstract Signaling pathways play an important role in cell fate determination in stem cells and regulate a plethora of developmental programs, the dysregulation of which can lead to human diseases. Growth factors (GFs) regulating these signaling pathways therefore play a major role in the plasticity...

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Principais autores: Sounak Sahu, Mary E. Albaugh, Betty K. Martin, Nimit L. Patel, Lisa Riffle, Susan Mackem, Joseph D. Kalen, Shyam K. Sharan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2022-05-01
Series:Scientific Reports
Acceso en liña:https://doi.org/10.1038/s41598-022-11224-6
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