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Monitoring of Leukemia Clones in B-cell Acute Lymphoblastic Leukemia at Diagnosis and During Treatment by Single-cell DNA Amplicon Sequencing

Acute lymphoblastic leukemia (ALL) is characterized by the presence of chromosomal changes, including numerical changes, translocations, and deletions, which are often associated with additional single-nucleotide mutations. In this study, we used single cell–targeted DNA sequencing to evaluate the c...

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Detalhes bibliográficos
Principais autores: Sarah Meyers, Llucia Alberti-Servera, Olga Gielen, Margot Erard, Toon Swings, Jolien De Bie, Lucienne Michaux, Barbara Dewaele, Nancy Boeckx, Anne Uyttebroeck, Kim De Keersmaecker, Johan Maertens, Heidi Segers, Jan Cools, Sofie Demeyer
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2022-04-01
Colecção:HemaSphere
Acesso em linha:http://journals.lww.com/10.1097/HS9.0000000000000700
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