Role of Histone Variant H2A.J in Fine-Tuning Chromatin Organization for the Establishment of Ionizing Radiation-Induced Senescence

Purpose: Radiation-induced senescence is characterized by profound changes in chromatin organization with the formation of <i>Senescence-Associated-Heterochromatin-Foci</i> (SAHF) and <i>DNA-Segments-with-Chromatin-Alterations-Reinforcing-Senescence</i> (DNA-SCARS). Importantly, senescent cells also...

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Huvudupphov:	Mutaz A. Abd Al-razaq, Benjamin M. Freyter, Anna Isermann, Gargi Tewary, Adèle Mangelinck, Carl Mann, Claudia E. Rübe
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2023-03-01
Serie:	Cells
Ämnen:	histone variant H2A.J ionizing radiation radiation-induced senescence Senescence-Associated Heterochromatin Foci (SAHF) DNA-Segments with Chromatin Alterations Reinforcing Senescence (DNA-SCARS) Senescence-Associated Secretory Phenotype (SASP)
Länkar:	https://www.mdpi.com/2073-4409/12/6/916
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