Inhibition of prejunctional parasympathetic pathways by β3-adrenoceptor agonists in the isolated pig detrusor: comparison with human detrusor studies

Adrenergic receptors of the β3-subtype (β3-ADRs) seem to represent a new target for a more effective pharmacological treatment of overactive bladder (OAB), a wide spread urinary disorder. A promising opportunity for OAB therapy might rely on the development of selective β3-ADR agonists, but an appro...

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Autori principali:	Gianluigi D’Agostino, Stefano Salvatore, Paolo Calvi, Anna Maria Condino
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2023-05-01
Serie:	Frontiers in Pharmacology
Soggetti:	acetylcholine release β3-ADR agonist porcine detrusor mirabegron OAB
Accesso online:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1177653/full
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