Characterization of drug responses of mini patient-derived xenografts in mice for predicting cancer patient clinical therapeutic response

Abstract Background Patient-derived organoids and xenografts (PDXs) have emerged as powerful models in functional diagnostics with high predictive power for anticancer drug response. However, limitations such as engraftment failure and time-consuming for establishing and expanding PDX models followe...

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Hlavní autoři:	Feifei Zhang, Wenjie Wang, Yuan Long, Hui Liu, Jijun Cheng, Lin Guo, Rongyu Li, Chao Meng, Shan Yu, Qingchuan Zhao, Shun Lu, Lili Wang, Haitao Wang, Danyi Wen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2018-09-01
Edice:	Cancer Communications
Témata:	Personalized cancer therapy Cancer precision medicine Patient-derived xenograft (PDX) MiniPDX Drug response In vivo
On-line přístup:	http://link.springer.com/article/10.1186/s40880-018-0329-5
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