IgG3 deficiency extends lifespan and attenuates progression of glomerulonephritis in MRL/<it>lpr </it>mice

<p>Abstract</p> <p>Background</p> <p>Antibodies of the IgG3 subclass have been implicated in the pathogenesis of the spontaneous glomerulonephritis observed in mice of the MRL/MpJ-Tnfrsf6<it>lpr </it>(MRL/<it>lpr</it>) inbred strain which have been widely studied as a model of systemic lupus erythem...

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Detalhes bibliográficos

Principais autores:	Greenspan Neil S, Lu Myro A, Shipley Jacob W, Ding Xuedong, Li Qing, Sultana Dilara, Kollaros Maria, Schreiber John R, Fu Pingfu, Putterman Chaim, Emancipator Steven N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2012-01-01
coleção:	Biology Direct
Acesso em linha:	http://www.biology-direct.com/content/7/1/3
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