The T Cell Receptor Repertoire in Neuropsychiatric Systemic Lupus Erythematosus

Objective: In systemic lupus erythematosus (SLE), widespread T cell infiltration into target organs contributes to inflammation and organ damage. Autoreactive T cells become aberrantly activated in this disease due to dysfunctional T cell receptor signaling that lowers the activation threshold. Char...

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Principais autores:	Erica Moore, Michelle W. Huang, Shweta Jain, Samantha A. Chalmers, Fernando Macian, Chaim Putterman
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2020-07-01
Series:	Frontiers in Immunology
Assuntos:	systemic lupus erythematosus MRL/lpr T cell receptor neuropsychiatric lupus choroid plexus salivary gland
Acceso en liña:	https://www.frontiersin.org/article/10.3389/fimmu.2020.01476/full
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