Short-Term Epileptiform Activity Potentiates Excitatory Synapses but Does Not Affect Intrinsic Membrane Properties of Pyramidal Neurons in the Rat Hippocampus In Vitro

Even brief epileptic seizures can lead to activity-dependent structural remodeling of neural circuitry. Animal models show that the functional plasticity of synapses and changes in the intrinsic excitability of neurons can be crucial for epileptogenesis. However, the exact mechanisms underlying epil...

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Principais autores:	Julia L. Ergina, Dmitry V. Amakhin, Tatyana Y. Postnikova, Elena B. Soboleva, Aleksey V. Zaitsev
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-10-01
coleção:	Biomedicines
Assuntos:	temporal lobe epilepsy hippocampus 4-aminopyridine epilepsy model long-term potentiation AMPA receptor
Acesso em linha:	https://www.mdpi.com/2227-9059/9/10/1374
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