Seizure-Induced Potentiation of AMPA Receptor-Mediated Synaptic Transmission in the Entorhinal Cortex

Excessive excitation is considered one of the key mechanisms underlying epileptic seizures. We investigated changes in the evoked postsynaptic responses of medial entorhinal cortex (ERC) pyramidal neurons by seizure-like events (SLEs), using the modified 4-aminopyridine (4-AP) model of epileptiform...

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Detalhes bibliográficos

Principais autores:	Dmitry V. Amakhin, Elena B. Soboleva, Julia L. Ergina, Sergey L. Malkin, Anton V. Chizhov, Aleksey V. Zaitsev
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-12-01
coleção:	Frontiers in Cellular Neuroscience
Assuntos:	temporal lobe epilepsy calcium-permeable AMPA receptor epileptiform activity entorhinal cortex seizure-like event synaptic plasticity
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fncel.2018.00486/full
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