Rapid and sustained T cell-based immunotherapy against invasive fungal disease via a combined two step procedure

IntroductionAspergillus fumigatus (Asp) infections constitute a major cause of morbidity and mortality in patients following allogeneic hematopoietic stem cell transplantation (HSCT). In the context of insufficient host immunity, antifungal drugs show only limited efficacy. Faster and increased T-ce...

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Detalhes bibliográficos

Principais autores:	Sabine Tischer-Zimmermann, Elisabeth Salzer, Tamires Bitencourt, Nelli Frank, Christine Hoffmann-Freimüller, Julia Stemberger, Britta Maecker-Kolhoff, Rainer Blasczyk, Volker Witt, Gerhard Fritsch, Wolfgang Paster, Thomas Lion, Britta Eiz-Vesper, René Geyeregger
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-04-01
coleção:	Frontiers in Immunology
Assuntos:	HSCT Aspergillus infections T-cell immunotherapy Aspergillus-specific T cells T-cell expansion cytokine secretion
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.988947/full
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