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Serendipitous Symptom Control: Allopurinol for Spasticity in a Case of SPG4‐Linked Hereditary Spastic Paraplegia—A Case Report

ABSTRACT In a patient with genetically confirmed SPG4–linked hereditary spastic paraplegia, initiation of allopurinol for asymptomatic hyperuricemia led to rapid and sustained improvement in lower limb spasticity, allowing marked reduction of antispasmodic therapy. This serendipitous finding suggest...

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Huvudupphov: Ziad W. Elmezayen, Hossam Salameh, Asem Afana, Anwar Zahran
Materialtyp: Artigo
Språk:Inglês
Utgiven: Wiley 2026-01-01
Serie:Clinical Case Reports
Ämnen:
Allupurinol
antispasmodic
hereditary spastic paraplegia
SPG4
Länkar:https://doi.org/10.1002/ccr3.71884
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