Serendipitous Symptom Control: Allopurinol for Spasticity in a Case of SPG4‐Linked Hereditary Spastic Paraplegia—A Case Report

ABSTRACT In a patient with genetically confirmed SPG4–linked hereditary spastic paraplegia, initiation of allopurinol for asymptomatic hyperuricemia led to rapid and sustained improvement in lower limb spasticity, allowing marked reduction of antispasmodic therapy. This serendipitous finding suggest...

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Autores principales:	Ziad W. Elmezayen, Hossam Salameh, Asem Afana, Anwar Zahran
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2026-01-01
Colección:	Clinical Case Reports
Materias:	Allupurinol antispasmodic hereditary spastic paraplegia SPG4
Acceso en línea:	https://doi.org/10.1002/ccr3.71884
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