Deletion Mutants of <i>Francisella</i> Phagosomal Transporters FptA and FptF Are Highly Attenuated for Virulence and Are Protective Against Lethal Intranasal <i>Francisella</i> LVS Challenge in a Murine Model of Respiratory Tularemia

<i>Francisella tularensis</i> (<i>Ft</i>) is a Gram-negative, facultative intracellular bacterium that is a Tier 1 Select Agent of concern for biodefense for which there is no licensed vaccine. A subfamily of 9 <i>Francisella</i> phagosomal transporter (<i>fpt</i>) genes belonging to the Major Facil...

Deskribapen osoa

Xehetasun bibliografikoak

Egile Nagusiak:	Brandi E. Hobbs, Courtney A. Matson, Vasileios I. Theofilou, Tonya J. Webb, Rania H. Younis, Eileen M. Barry
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2021-06-01
Saila:	Pathogens
Gaiak:	<i>Francisella tularensis</i> Live Vaccine Strain (LVS) live attenuated vaccine MFS transporter attenuation organ burdens
Sarrera elektronikoa:	https://www.mdpi.com/2076-0817/10/7/799
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!