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Nrf1 and Nrf2 transcription factors regulate androgen receptor transactivation in prostate cancer cells.

Despite androgen deprivation therapy (ADT), persistent androgen receptor (AR) signaling enables outgrowth of castration resistant prostate cancer (CRPC). In prostate cancer (PCa) cells, ADT may enhance AR activity through induction of oxidative stress. Herein, we investigated the roles of Nrf1 and N...

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Detaylı Bibliyografya
Asıl Yazarlar: Michelle A Schultz, Sharika S Hagan, Amrita Datta, Yiguo Zhang, Michael L Freeman, Suresh C Sikka, Asim B Abdel-Mageed, Debasis Mondal
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2014-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:http://europepmc.org/articles/PMC3899380?pdf=render
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