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IFITM1-targeted NIR-II fluorescence imaging enables visualisation of colorectal cancer and metastatic lymph nodes

Abstract Background To improve the visualisation of colorectal cancer (CRC) and its metastatic lymph nodes (LNs), we developed a second near-infrared window (NIR-II; 1000–1700 nm) fluorescent probe using a monoclonal antibody against interferon-induced transmembrane protein 1 (IFITM1). The NIR-II of...

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Sábháilte in:
Príomhchruthaitheoirí: Shangkun Jin, Ruirong Lin, Shen Guan, Jiantao Jiang, Hongxin He, Enhao Wei, Ziyuan Lv, Weijin Yang, Jingtao Huang, Shiyao Zheng, Zhihua Zhou, Ruru Ge, Xiaohua Jia, Chunkang Yang
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2026-03-01
Sraith:Journal of Translational Medicine
Ábhair:
Colorectal cancer
Metastatic lymph nodes
Near-infrared II fluorescence imaging
Molecular imaging
Interferon-induced transmembrane protein 1
Rochtain ar líne:https://doi.org/10.1186/s12967-026-07938-0
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