IFITM1-targeted NIR-II fluorescence imaging enables visualisation of colorectal cancer and metastatic lymph nodes

Abstract Background To improve the visualisation of colorectal cancer (CRC) and its metastatic lymph nodes (LNs), we developed a second near-infrared window (NIR-II; 1000–1700 nm) fluorescent probe using a monoclonal antibody against interferon-induced transmembrane protein 1 (IFITM1). The NIR-II of...

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Hlavní autoři:	Shangkun Jin, Ruirong Lin, Shen Guan, Jiantao Jiang, Hongxin He, Enhao Wei, Ziyuan Lv, Weijin Yang, Jingtao Huang, Shiyao Zheng, Zhihua Zhou, Ruru Ge, Xiaohua Jia, Chunkang Yang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2026-03-01
Edice:	Journal of Translational Medicine
Témata:	Colorectal cancer Metastatic lymph nodes Near-infrared II fluorescence imaging Molecular imaging Interferon-induced transmembrane protein 1
On-line přístup:	https://doi.org/10.1186/s12967-026-07938-0
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