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Multi-step recognition of potential 5' splice sites by the Saccharomyces cerevisiae U1 snRNP

In eukaryotes, splice sites define the introns of pre-mRNAs and must be recognized and excised with nucleotide precision by the spliceosome to make the correct mRNA product. In one of the earliest steps of spliceosome assembly, the U1 small nuclear ribonucleoprotein (snRNP) recognizes the 5' splice...

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Autors principals: Sarah R Hansen, David S White, Mark Scalf, Ivan R Corrêa, Lloyd M Smith, Aaron A Hoskins
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications Ltd 2022-08-01
Col·lecció:eLife
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Accés en línia:https://elifesciences.org/articles/70534
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