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Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins

Early and persistent activation of complement is considered to play a key role in the pathogenesis of COVID-19. Complement activation products orchestrate a proinflammatory environment that might be critical for the induction and maintenance of a severe inflammatory response to SARS-CoV-2 by recruit...

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Gardado en:
Principais autores: Youssif M. Ali, Matteo Ferrari, Nicholas J. Lynch, Sadam Yaseen, Thomas Dudler, Sasha Gragerov, Gregory Demopulos, Jonathan L. Heeney, Wilhelm J. Schwaeble
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Assuntos:
complement system
lectin pathway
SARS-CoV-2
COVID-19
innate immunity
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fimmu.2021.714511/full
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