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FADD is a key regulator of lipid metabolism

Abstract FADD, a classical apoptotic signaling adaptor, was recently reported to have non‐apoptotic functions. Here, we report the discovery that FADD regulates lipid metabolism. PPAR‐α is a dietary lipid sensor, whose activation results in hypolipidemic effects. We show that FADD interacts with RIP...

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Kaydedildi:
Asıl Yazarlar: Hongqin Zhuang, Xueshi Wang, Daolong Zha, Ziyi Gan, Fangfang Cai, Pan Du, Yunwen Yang, Bingya Yang, Xiangyu Zhang, Chun Yao, Yuqiang Zhou, Chizhou Jiang, Shengwen Guan, Xuerui Zhang, Jing Zhang, Wenhui Jiang, Qingang Hu, Zi‐Chun Hua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Nature 2016-06-01
Seri Bilgileri:EMBO Molecular Medicine
Konular:
FADD
lipid metabolism
obesity
PPAR‐α
Online Erişim:https://doi.org/10.15252/emmm.201505924
Etiketler: Etiketle
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