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FADD is a key regulator of lipid metabolism

Abstract FADD, a classical apoptotic signaling adaptor, was recently reported to have non‐apoptotic functions. Here, we report the discovery that FADD regulates lipid metabolism. PPAR‐α is a dietary lipid sensor, whose activation results in hypolipidemic effects. We show that FADD interacts with RIP...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Hongqin Zhuang, Xueshi Wang, Daolong Zha, Ziyi Gan, Fangfang Cai, Pan Du, Yunwen Yang, Bingya Yang, Xiangyu Zhang, Chun Yao, Yuqiang Zhou, Chizhou Jiang, Shengwen Guan, Xuerui Zhang, Jing Zhang, Wenhui Jiang, Qingang Hu, Zi‐Chun Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Nature 2016-06-01
Schriftenreihe:EMBO Molecular Medicine
Schlagworte:
FADD
lipid metabolism
obesity
PPAR‐α
Online-Zugang:https://doi.org/10.15252/emmm.201505924
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