Post-randomization Biomarker Effect Modification Analysis in an HIV Vaccine Clinical Trial

While the HVTN 505 trial showed no overall efficacy of the tested vaccine to prevent HIV infection over placebo, markers measuring immune response to vaccination were strongly correlated with infection. This finding generated the hypothesis that some marker-defined vaccinated subgroups were partiall...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Gilbert Peter B., Blette Bryan S., Shepherd Bryan E., Hudgens Michael G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	De Gruyter 2020-07-01
coleção:	Journal of Causal Inference
Assuntos:	principal stratification randomized clinical trial two-phase sampling
Acesso em linha:	https://doi.org/10.1515/jci-2019-0022
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!