Post-randomization Biomarker Effect Modification Analysis in an HIV Vaccine Clinical Trial
While the HVTN 505 trial showed no overall efficacy of the tested vaccine to prevent HIV infection over placebo, markers measuring immune response to vaccination were strongly correlated with infection. This finding generated the hypothesis that some marker-defined vaccinated subgroups were partiall...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
De Gruyter
2020-07-01
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| Serie: | Journal of Causal Inference |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1515/jci-2019-0022 |
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