Targeting platelet-tumor cell interactions via thromboxane A2-prostanoid receptor blockade to reduce metastasis in triple negative breast cancer

Abstract In addition to their central role in blood hemostasis, it is increasingly clear that platelets contribute to multiple steps in the metastatic cascade. Platelets are one of the most abundant cells with which tumor cells interact once they enter the circulation, and the interaction of platele...

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Autors principals:	Veeresh Toragall, Ann C. Rester, Salma Begum, Oluwaseyi T. Shofolawe-Bakare, Kenneth Hulugalla, Jerry D. Monroe, John P. Bentley, Yann Gibert, Thomas A. Werfel
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-11-01
Col·lecció:	Experimental Hematology & Oncology
Matèries:	Ifetroban Platelet activation Thromboxane receptor and antimetastatic efficacy
Accés en línia:	https://doi.org/10.1186/s40164-025-00723-7
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