Epigenetic modifications in KDM lysine demethylases associate with survival of early-stage NSCLC

Abstract Background KDM lysine demethylase family members are related to lung cancer clinical outcomes and are potential biomarkers for chemotherapeutics. However, little is known about epigenetic alterations in KDM genes and their roles in lung cancer survival. Methods Tumor tissue samples of 1230...

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Autori principali:	Yongyue Wei, Junya Liang, Ruyang Zhang, Yichen Guo, Sipeng Shen, Li Su, Xihong Lin, Sebastian Moran, Åslaug Helland, Maria M. Bjaanæs, Anna Karlsson, Maria Planck, Manel Esteller, Thomas Fleischer, Johan Staaf, Yang Zhao, Feng Chen, David C. Christiani
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2018-04-01
Serie:	Clinical Epigenetics
Soggetti:	KDM Lysine demethylase DNA methylation Lung cancer Survival
Accesso online:	http://link.springer.com/article/10.1186/s13148-018-0474-3
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