Immunophenotyping TCF1-expressing TILs: spatial profiling and prognostic value in operable non-small cell lung cancer

BackgroundThe spatial distribution and functional heterogeneity of tumor-infiltrating lymphocytes (TILs) significantly impact patient outcomes in non-small cell lung cancer (NSCLC). While T cell factor 1 (TCF1) expressing TILs have emerged as key players in sustaining anti-tumor immunity, their subs...

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Detalles Bibliográficos

Principais autores:	Konstantinos Ntostoglou, Georgios Christodoulopoulos, Katie Stoker, Jean Descarpentrie, Anastasia Xagara, Dora Chatzidaki, Vasiliki Anastasopoulou, Ilias P. Nikas, Argyro Ioanna Ieronimaki, Lucy Booth, Sophia Tsoka, Ioannis Vamvakaris, Apostolos Klinakis, Eleni Patsea, Sophia N. Karagiannis, Ioannis G. Panayiotides, Teresa Frisan, Vassilis Georgoulias, Athanasios Kotsakis, Ioannis S. Pateras
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2026-01-01
Series:	Frontiers in Immunology
Assuntos:	biomarkers non-small cell lung cancer spatial analysis T cell factor 1 tumor infiltrating lymphocytes tumor microenvironment
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1731337/full
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