Quercetin inhibits angiotensin II-induced vascular smooth muscle cell proliferation and activation of JAK2/STAT3 pathway: A target based networking pharmacology approach

The rapid growth of vascular smooth muscle cells (VSMCs) represents crucial pathological changes during the development of hypertensive vascular remodeling. Although quercetin exhibits significantly therapeutic effects on antihypertension, the systematic role of quercetin and its exact mode of actio...

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Hlavní autoři:	Di Wang, Farman Ali, Huixin Liu, Ying Cheng, Meizhu Wu, Muhammad Zubair Saleem, Huifang Zheng, Lihui Wei, Jiangfeng Chu, Qiurong Xie, Aling Shen, Jun Peng
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-10-01
Edice:	Frontiers in Pharmacology
Témata:	networking pharmacology JAK2 quercetin vascular smooth muscle cells stat3
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2022.1002363/full
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